Analyses of products with Cannabinoids

Microbiological and chemical analyses of Cannabinoids in different products
(Oils, extracts and crystals from plants such as Cannabis, cosmetic and personal care products, medical devices, foodstuffs, food supplements and others).

Indicator Testing method Accreditation under

ISO/IEC 17025**

Microbiological indicators
Total Aerobic Microbial Count (TAMC) Ph. Eur. 2.6.12,

Ph. Eur. 2.6.31

BDS EN ISO 21149

Total Yeast and Mold Count (TYMC) Ph. Eur. 2.6.12,

Ph. Eur. 2.6.31

BDS EN ISO 16212

Bile-tolerant gram-negative bacteria Ph. Eur. 2.6.13,

Ph. Eur. 2.6.31

Salmonella spp / Salmonella Ph. Eur. 2.6.13,

Ph. Eur. 2.6.31

Escherichia coli Ph. Eur. 2.6.13,

Ph. Eur. 2.6.31

BDS EN ISO 21150

Candida albicans Ph. Eur. 2.6.13
Staphylococcus aureus Ph. Eur. 2.6.13

BDS EN ISO 22718

Pseudomonas aeruginosa Ph. Eur. 2.6.13
Clostridia Ph. Eur. 2.6.13
Preservative challenge test BDS EN ISO 11930
Preservative challenge test for cannabinoids-based products Depending on the product
Chemical indicators
Quantitative determination of Cannabinoids

Cannabidiol (CBD)

Cannabidiolic acid (CBDA)

Tetrahydrocannabinol (THC)

Tetrahydrocannabinolic acid (THCA)

Cannabinol (CBN)

Cannabigerol (CBG)

Cannabigerolic acid (CBGA)

Cannabichromene (CBC)

Quantitative determination of Tetrahydrocannabinol (THC) in leaf samples 0014-ILM-GT, based on

Regulation (EU) 2017/1155)

Metal content

Lead (Pb), Cadmium (Cd), Zinc (Zn), Copper (Cu), Iron (Fe), Magnesium (Mg), Calcium (Ca), Arsenic (As), Phosphorus (P), Mercury (Hg), Manganese (Mn)


Water soluble and fat soluble



Pesticides & PCB BDS EN 15662;

CD CEN/TS 17062


Anisidine value Ph. Eur. 2.5.36
Acid value

(for samples containing fats)

Ph. Eur. 2.5.1
Peroxide value

(for samples containing fats)

Ph. Eur. 2.5.1
Тotal oxidation value (TOTOX) USP <401>
Stability study ICH Topic Q 1 A (R2)

/ or other applicable procedure

**Due to the specifics in performing the analyses in this category and due to the variety of products with cannabinoids, the above analyses for each product must be initially confirmed by TC Globaltest.

Important – Δ9-tetrahydrocannabinol (THC) analyses
All activities carried out at IC GLOBALTEST LTD with substances categorized as narcotic, according to the Bulgaria’s Law of control of narcotic substances and precursors (LCNSP), are subject to reporting and audit to / from the Ministry of Health of Republic of Bulgaria. No information received or created during the performance of laboratory activities in connection with analyzes under the LCNSP will be kept confidential before the Ministry of Health and official agencies and institutions conducting audits and verifications of analyzes under the LCNSP or other applicable laws. No confidentiality clauses in this case apply.

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