Microbiological and chemical analyses of Cannabinoids in different products
(Oils, extracts and crystals from plants such as Cannabis, cosmetic and personal care products, medical devices, foodstuffs, food supplements and others).
| Indicator | Testing method | Accreditation under
ISO/IEC 17025** |
| Microbiological indicators | ||
| Total Aerobic Microbial Count (TAMC) | Ph. Eur. 2.6.12,
Ph. Eur. 2.6.31 BDS EN ISO 21149 |
√ |
| Total Yeast and Mold Count (TYMC) | Ph. Eur. 2.6.12,
Ph. Eur. 2.6.31 BDS EN ISO 16212 |
√ |
| Bile-tolerant gram-negative bacteria | Ph. Eur. 2.6.13,
Ph. Eur. 2.6.31 |
√ |
| Salmonella spp / Salmonella | Ph. Eur. 2.6.13,
Ph. Eur. 2.6.31 |
√ |
| Escherichia coli | Ph. Eur. 2.6.13,
Ph. Eur. 2.6.31 BDS EN ISO 21150 |
√ |
| Candida albicans | Ph. Eur. 2.6.13 | √ |
| Staphylococcus aureus | Ph. Eur. 2.6.13
BDS EN ISO 22718 |
√ |
| Pseudomonas aeruginosa | Ph. Eur. 2.6.13 | √ |
| Clostridia | Ph. Eur. 2.6.13 | √ |
| Preservative challenge test | BDS EN ISO 11930 | √ |
| Preservative challenge test for cannabinoids-based products | Depending on the product | – |
| Chemical indicators | ||
| Quantitative determination of Cannabinoids
Cannabidiol (CBD) Cannabidiolic acid (CBDA) Tetrahydrocannabinol (THC) Tetrahydrocannabinolic acid (THCA) Cannabinol (CBN) Cannabigerol (CBG) Cannabigerolic acid (CBGA) Cannabichromene (CBC) |
0014-ILM-GT | √ |
| Quantitative determination of Tetrahydrocannabinol (THC) in leaf samples | 0014-ILM-GT, based on
Regulation (EU) 2017/1155) |
√ |
| Metal content
Lead (Pb), Cadmium (Cd), Zinc (Zn), Copper (Cu), Iron (Fe), Magnesium (Mg), Calcium (Ca), Arsenic (As), Phosphorus (P), Mercury (Hg), Manganese (Mn) |
0031-ILM-GT | √ |
| Vitamins
Water soluble and fat soluble |
0497-ILM-GT
0498-ILM-GT |
√ |
| Pesticides & PCB | BDS EN 15662;
CD CEN/TS 17062 0479-ILM-GT |
√ |
| Anisidine value | Ph. Eur. 2.5.36 | – |
| Acid value
(for samples containing fats) |
Ph. Eur. 2.5.1 | – |
| Peroxide value
(for samples containing fats) |
Ph. Eur. 2.5.1 | – |
| Тotal oxidation value (TOTOX) | USP <401> | – |
| Stability study | ICH Topic Q 1 A (R2)
/ or other applicable procedure |
|
**Due to the specifics in performing the analyses in this category and due to the variety of products with cannabinoids, the above analyses for each product must be initially confirmed by TC Globaltest.
Important – Δ9-tetrahydrocannabinol (THC) analyses
All activities carried out at IC GLOBALTEST LTD with substances categorized as narcotic, according to the Bulgaria’s Law of control of narcotic substances and precursors (LCNSP), are subject to reporting and audit to / from the Ministry of Health of Republic of Bulgaria. No information received or created during the performance of laboratory activities in connection with analyzes under the LCNSP will be kept confidential before the Ministry of Health and official agencies and institutions conducting audits and verifications of analyzes under the LCNSP or other applicable laws. No confidentiality clauses in this case apply.